After a childhood prank by his brother Angus causes Henry to develop a phobia of sheep, he must step up to the onslaught of a genetically-mutated man-eating flock with the help of his friend and a young environmentalist.

A young scientist who is convinced that a dangerous new pathogen threatens the population and tracks it back to her hometown – which is located in the shadow of the remote sheep station where the macabre events of the original Black Sheep unfolded.