Victor Reynolds arrives at the notorious House of Usher, whereupon he is greeted by old acquaintances Roderick and Madeline Usher and their servant, Markus. As Victor uncovers more about the history of the house and the disappearances of those that entered it previously, he begins to realize that he is in mortal danger.

Seven students answer an advertisement to participate in an experiment to explore how the sensation of pain can be eliminated. Arriving at a secluded institute, they are welcomed by mysterious scientist JB Divay. Initially, JB's fascination with hypnosis, clocks and cactus plants are dismissed by the group as mere eccentricities. But as the students begin to disappear one by one, they begin to question JB's true intentions.

In this update to Edgar Allan Poe's classic tale, it's time for the biggest gay party of the year. Unfortunately, the host has chosen the site of the infamous Ravenswood Massacre to stage his blowout gala, where a mass murder happened fifty years ago to the night. The boozie revelry is cut short when a Raven-masked killer crashes the party, intent on repeating the bloody history. As the unknown killer picks the guests off, old grudges resurface among friends, and new suspicions emerge.