In late 1960s New York City, fed up with monotonous college life and police repression, free-spirited Fritz, an impenitent seducer and unrestrained party-animal, decides to explore the world. And just like that, as he flees NYC, heading to San Francisco, Fritz embarks on an endless adventure of illumination. Immersed in a world surrounded by drugs and sex, Fritz participates in mad orgies, brings about a revolution, incites mass urban riots, and crosses paths with drug-addled Nazi bikers.

Fritz, now married and a father, is desperate to escape the domestic hell he now finds himself in. Lighting up a joint, he begins to dream about his eight other lives, hoping to find one to provide a pleasant distraction. The drug-induced journeys he takes include spells as an astronaut, Hitler's psychiatrist, a courier travelling in hostile territory during a race war, and as a pupil of an Indian guru in the sewers of New York.