On a historic night where Jimmy Kimmel has previously debuted such pieces as the "I'm F@#%-ing Ben Affleck" music video and "Mel Gibson's The Colonel", he introduced a new star-studded video including Jimmy and 15 of the most handsome men in Hollywood who come together for the handsomest gathering ever. Jimmy also welcomed two-time Academy Award® nominee Robert Downey, Jr. who presented the world premiere of the new Iron Man 2 trailer, and a musical performance by Grammy Award® winner Keith Urban. Plus special appearances by Ben Affleck, Jennifer Garner, Matthew McConaughey, Patrick Dempsey, Sting, and many more.