Jamie and Sarah Powell have a school-project that involves raising eggs as children. Real eggs, not so real children. It's suppose to teach the girls about responsibility. The girls get involved in the concept and it brings the attention of the whole family to child rearing. Even Charles tries to help, after all, he is a professional in this field, watching the Powell kids for his room and board. Meanwhile, Walter Powell is taking out a long lost sweetheart, Gloria (Betsy Palmer). When Buddy meets Gloria, he is less then thrilled, because she turns out to be his grandmother. All's well that ends well. And in the meantime, the kids learn more about families and friends, than their eggs, and Buddy learns tolerance - sort of. But as usual, everything is scrambled, eggs and people. That's what happens on "Charles in Charge."