Gabimaru, a ninja member of a clan of assassins, is sentenced to death. He claims to have nothing to tie him to life, yet no method of execution manages to end his life. His meeting with Sagiri Yamada Asaemon, who seems to be investigating him, will change everything.

Gabimaru is introduced to the shogun along with other criminals selected to travel by boat to the Divine Land to search for the elixir of immortality. Under the supervision of the samurai of the Yamada clan, they are told the rules that will govern their journey, before moving on to the brutal selection of participants.

The death row inmates and their guards enter the mystical island, where magnificent flowers grow and unusual insects swarm around. But there isn't much time to admire the scenery, as some criminals don't intend to play by the rules.

Gabimaru and Sagiri are in trouble during their first fight against the island's mysterious creatures. Gabimaru is unaware of these monstrosities and this puts him at a disadvantage in battle. The sudden arrival of Yuzuriha, the female ninja, will change the situation, but Gabimaru does not see clearly in her game.

Sagiri comes to her senses in a cave on the island. His companions share their knowledge of the island to determine what to do next. As they prepare to spend the night, Genji, one of the samurai, offers Sagiri to leave the island on his boat, claiming that this mission is not suitable for a woman like her.

Rokurota starts to cause serious problems for Sagiri and Gabimaru, and now they must think of a strategy to defeat him!

Sagiri and Gabimaru's group discovers a village that turns out not to be completely abandoned, and Chobe and Toma stumble upon some beings that turn out not to be angelic.

Tenza and Nurugai continue their inspection of the coasts in order to find a current which would allow a boat to move away from the island, but they come face to face with an Eternal. They manage to get away and meet Shion, the master of Tenza at the Asaemon.

Gabimaru leaves his group behind to go to Hôrai to find the elixir. But a door stands between him and his objective, and to cross it he must face Zhu Jin, one of the Eternals.

Gabimaru finds himself face to face with Gantetsusai and Fuchi Yamada Asaemon. He knows that the fight will be tough and prefers to change strategy to keep his chances of finding the elixir. In Sagiri's group, Senta uses the information given by Hôko to refine his vision of the island.

After Chobe and Toma, it's the turn of Gabimaru's group to come face to face with a monk. The latter asks Mei to follow him to return to a place he calls the “palace”. When the monk explains what he intends to do to the girl, Gabimaru and Gantetsusai decide to protect her, even if it goes against the habits of the ninja.

Barely arriving in Horai, Sagiri, Yuzuriha, and Senta find themselves facing a Tensen. He makes them a revelation that will question the purpose of their mission, but before thinking about what's next, they must find a way to eliminate this impressive enemy.

Aided by Sagiri and Nurugai, Shion faces the Celestial Guru Mu Dan in his Kishikai form, armed with his knowledge of wave management and the Tao. Meanwhile, Gabimaru reawakens in a remote cave with no memory of what happened...