Disaster strikes when the All Saints emergency team is caught in the collapse of a nightclub while celebrating New Year's Eve. Cate stands by Mac when he is crushed by falling debris and is horrified to learn that his injuries may be permanent. Terry, having averted the disaster by half an hour, finally puts an end to the uncertainty for Jack and Charlotte. Meanwhile, Dan is trapped with a young woman who is critically injured.

A tragic accident brings Frank's ex-wife into the ED as his worst nightmare confronts him. The ED staff is stunned to learn that Frank has a daughter. As Mac faces the possibility of life in a wheelchair, Gill and Cate try to come to terms with it. Jack comes to an uneasy truce with Charlotte and his impending fatherhood, while Dan helps two young girls at the nightclub before they face the disastrous consequences of their choices.

Cate's mission to save a child forced in to prostitution is reignited when her madame mother is brought into All Saints brutally bashed. Jack's encounter with a woman injured after a deadly road rage incident makes him re-evaluate his own behaviour. When Frank learns Kathleen's mother has been to see her several times, an angry confrontation settles nothing.

Jack's journey of self discovery opens old wounds that reveal how he really feels about fatherhood. A patient covered in blood collapses in the waiting room and Dan is lead down a path of mystery and murder. A high speed police chase involving a stolen car leads to a horrific car accident. When Frank loses the battle to save one of the young men it brings him into conflict with the police. Cate struggles to deal with her own emotions as Mac reluctantly faces his first rehab session.

Vincent and Cate work together to save a critically injured construction worker, his wife's emotional instability threatens to throw them both off balance. Nelson faces his inner demons when he discovers a six year old girl, near death, locked in a car outside a pub on a blistering summer's day. Cate's future with Mac is threatened by the arrival of a surprise visitor.

Charlotte is sent sprawling by a hit and run driver and fights to save her unborn child. Things with Mac are coming to a head for Cate. She suspects that he's on the verge of a decision that will send him back into arms of Gill - breaking her heart. Jessica's high-spirited but difficult bipolar patient refuses to medicate himself, but when he lets slip that he had a couple of car accidents earlier in the day her curiosity is piqued.

In the aftermath of Charlotte's miscarriage, Terri returns to All Saints to a cold reception from Jack. In this bitter mood, Jack has little patience for a man brought in with septic shock from self-inflicted wounds following the death of his twin brother. Unable to engage emotionally with the grieving man, Jack pushes to have the patient treated against his wishes. Cate refuses to let Jack allow his own pain to compromise his usual compassion.

Frank, in trying to save the victim of a motorbike accident that could be a suicide attempt, and dealing with the victim's distressed relatives, is given fresh insight into his own domestic situation. Jessica, intrigued by the repeated ED admissions of a 16-year-old schoolboy, unwittingly fuels the crush he develops on her as she pushes to identify his condition. Dan, nursing a patient who effectively talks himself into a heart attack, does his best to help the guy understand the importance of letting go of the past.

Vincent and Charlotte find themselves at loggerheads when Beth is admitted to All Saints, while Terri and Jack get more than they bargain for when they treat a woman who has exorcised her son. Elsewhere, Von's plan to buy a house hits an obstacle when she is knocked back for a housing loan.

Cate is forced to confront her feelings about Mac's decision to leave and, through an encounter with a grieving widow, learns to let go. While All Saints radiographers are on strike, tensions run high in emergency and Terri has to get tough with the department's men. Dan grapples with his expectations of mateship when his best friend hits it off with Jessica. Charlotte begins to realise that Vincent is moving on.

A car explosion rocks a local supermarket, sending waves of paranoia through the community. The question on everyone's lips is - was it terrorism? The truth is eventually uncovered but it comes at a high price. Meanwhile, Vincent is dealing with demons of his own while trying to anticipate Beth's next move.

Regina struggles to keep a promise to a dying friend. Meanwhile, Jack triumphs over a complicated and life-threatening case and in the process wins the respect and friendship of the younger staff members. Elsewhere, Charlotte and Vincent get more than they bargained for on a night out, while Dan feels a tinge of jealousy at Jessica and Stuart's growing friendship

A road accident brings Terri face to face with her past, and Charlotte has to heal a relationship and a patient. Meanwhile, Vincent is confronted by Beth's terrorism, and Von finds a family member back in her life.

Charlotte's faith in Vincent is tested when he is arrested for assaulting Beth Chandler. After a violent incident at a brothel, everyone involved ends up in the ED. Terri reaches an understanding with Jack after they spend the day with Mitch's daughter Lucy.

Vincent, accused of stalking and charged with assault, faces a hostile court hearing. Cate comes under fire professionally and faces a career crisis. Meanwhile, Terri is asked to make the promise of a lifetime.

Terri's day in Emergency is over shadowed when Mitch's mother, Victoria undergoes a life-threatening operation. Von is unhappy when she suspects a relationship is developing between Nelson and Kerry. Charlotte is reminded of the tragedy of her miscarriage when she treats a six-month-old baby.

Terri decides to work part-time so that she can care for Mitchs daughter leaving her job up for grabs.

Terri redefines her own future when nursing a young girl who believes she no longer has a future of her own.

Terri spends her last day on a crusade to alleviate a young girl's guilt and Beth's jealousy spirals out of control.

In the aftermath of Beth's car bomb, Vincent feels the burden of guilt and Jessica is honest with Stuart as to why they broke up.

Beth continues to wreak havoc on the lives of those close to Vincent and Cate makes a disastrous error of judgement.

Charlotte and Jack fight for the lives of a young couple and their unborn child and Vincent is close to breaking point.

Nelson and Vincent put their lives in danger, treating a highly contagious patient.

Vincent is forced to go to extraordinary lengths to avoid tragedy as Beth makes her final move.

When a wild time turns tragic for a carload of teenagers, Dan is faced with ghosts from the past.

Stuart's spiraling out of control and Dan is helpless to stop him. Cate gives Vincent an ultimatum.

When a gunman runs rampant in a local supermarket, Dan and Jess are caught in the crossfire with a dying man.

The police deliver a badly beaten and mutilated drug informant into the Emergency Department, putting the whole department at risk.

When a light plane crashes on the outskirts of the city, Cate is confronted with issues from the past.

When an illegal drag sees a young man badly injured, Cate and Vincent fight for his life.

When rival bikie gangs hit the Emergency Department, Frank and Dan are left to deal with a war zone.

Tensions run high in the Emergency Dept when Charlotte and Von struggle to deal with a psychotic patient.

Jack has a mind-blowing confrontation with his past, forcing him to face his future.

Nelson and Jess are thrown in the deep end when the condition of a patient takes an unexpected turn.

Jack wrestles with a medical mystery when a woman presents asthmatic symptoms.

A spectacular storm plunges All Saints into darkness. Spence turns up in the ED sending Charlotte and Vincent into a spin.

A man falls from the Hospitals balcony and the team fight for his life. But did he fall?

When a tunnel collapses, tensions mount as Vincent questions Cate's allegiance.

The ED team fights for a man's life after he is savaged by guard dogs. Charlotte struggles with the most tempting offer.

Charlotte and Vincent go head to head over a patient's treatment while Jack tackles a post op patient threatening to sue.

Wedding bells are ringing but not one of the All Saints team is prepared for the tragic events that are about to unfold.