Michael and K.I.T.T.'s latest assignment, to guard a volatile new isotope in Chicago, looks as if it could be their last, when the late Wilton Knight's daughter Jennifer plans to shut down their division of FLAG, and suspends Michael. But meanwhile, international terrorist Phillip Nordstrom kidnaps Devon, and uses hi-tech laser surgery on a criminal to create an impostor, as part of Nordstrom's plot to get his hands on the valuable isotope. Even though suspended, Michael becomes suspicious of (the impostor) Devon's behaviour and investigates — but Nordstrom plans to get rid of their interference, coating K.I.T.T. in a chemical to break down his molecular amour coating, before turning loose "The Juggernaut" — a deadly mobile battering ram...

With K.I.T.T. completely wrecked by Nordstrom's "Juggernaut" battering ram, Michael and Bonnie, unable to turn to the strangely behaving Devon, enlist a street gang headed by a vigilante known as "The Street Avenger" to rebuild K.I.T.T. in a back-street garage, adding some key new features in the process; but it's a race against the clock to rebuild K.I.T.T. in time to prevent Nordstrom stealing the isotope...

With Michael closing in on a master criminal who has escaped capture for years, the man and his henchmen plot to slow Michael up by trapping K.I.T.T. ...

Bonnie's plane is hijacked and the passengers are held hostage by an ex-intelligence agent who wants money and "political" prisoners set free.

An archaeologist excavating an ancient burial ground is kidnapped by a man who gets the oil-rich Indian land if no artifacts are found.

When a biker gang hi-jack and steal the FLAG truck, hospitalising RC3 in the process, they expect it to be full of liquor - so are amazed to find it full of computer equipment. The son of two computer experts, himself a computer genius, is persuaded into helping the gang to use the truck's advanced technology to aid them on a crime spree. Michael and K.I.T.T. must stop the gang before they use the computers to disrupt the test-run of a new computerised vehicle that is armed with a warhead...

Bonnie poses as a jetsetter to gain access to a foreign embassy planning to ship a canister of deadly bacteria out of the country.

Michael's well-deserved break for his birthday is interrupted when Devon assigns him to find a stolen hi-tech hovercraft prototype before a black market arms dealer can ship it out of the country...

Someone tries to kill Michael after he qualifies to drive for an independent racing team plagued by a series of "accidents".

Michael discovers that prison inmates were used to steal security plans for a hotel that is hosting a defense conference.

A childhood friend of RC3's is involved with a blockbusting real-estate developer, who's trying to prevent the opening of a nightclub that could revitalize RC3's old neighborhood.

After a near-fatal encounter with a criminal mastermind, Michael falls into a deep depression and wants to quit the Foundation. He and Stevie are married.

An embittered electronics genius gains control of KITT's programming and turns the car on Michael.

A family logging outfit is unable to sell its timber because the local sawmill is buying pirated timber that was out on national park land.

When a Foundation trustee is murdered, Michael's prime suspects master magician Austin Templeton — but the man was seemingly on stage performing at the time of the murder. Michael is determined to prove that Templeton used his "magical" trickery to fool the audience and give him the perfect alibi. The fact that Bonnie, an old flame of Templeton's, was in the audience and is insistent of his innocence, does not make the case any easier...

When a sports promoter who claims to have some incriminating information about a legendary boxing match is murdered, Michael investigates an upcoming fight involving a villainous promoter and a former boxing champ who is determined to step back into the ring even if it kills him...

After a wanted mobster escapes an F.B.I. raid, murdering an Agent friend of Michael's in the process, Michael and K.I.T.T., backed up by RC3, follow a secret dune-buggy race in which the mobster is racing to make his escape across the border into Mexico, where a new identity awaits him...

Michael and K.I.T.T. have the seemingly easy, relaxing job of patrolling a national park for a couple of days, when they find themselves up against an arsonist driving an All-Terrain Vehicle, who escapes over rough terrain that K.I.T.T. can't cover. As they investigate to find just who is behind the spate of arson attacks, Michael must prove the innocence of a teenage boy, a reformed vandal, who is being framed for starting the fires...

Michael is captured while trying to rescue an American political prisoner held in a country in the throes of a coup d'etat.

Inexplicable accidents on a movie set are blamed on a legendary phantom haunting the studio.

A powerful Japanese businessman attempts to abduct the adopted son of Devon's friend because the boy is a direct descendent of the founder of an ancient terrorist cult.

Intercepting a robbery, Michael is shocked when one of the thieves apparently commits suicide, jumping out of a high-rise window. Investigating, it emerges that a con woman posing as a voodoo princess is using special earclips that cause the wearers to become zombified slaves to her commands. The woman plans to use her entranced henchmen to steal her some priceless archaeological finds, but in trying to stop the plot, Michael himself falls under the spell of one of the earclips....