Newspaper columnist Hedda Hopper comes to the Ricardos' home in Connecticut to interview them about how they met. They then weave the tale about how Lucy and her best friend, Susie MacNamara, went on a cruise to Havana and Ricky and Rudy Vallee caught their eye. After much adventure, Lucy and Susie must figure out a way to get Ricky and Rudy to America.

Lucy and Ethel find out they have a new next-door neighbor moving in. When she comes to use their telephone, they find it's none other than Tallulah Bankhead, prolific stage and film actress. Suddenly, Lucy realizes this means she has a chance at getting Bankhead to appear at her local PTA benefit. To impress the star, she invites her to dinner, conning the Mertzes into posing as her hired help. The meal and a series of meetings after it, creates a riff between Ms. Bankhead and Lucy. With this riff, who will perform at the PTA benefit?

The Ricardos and the Mertzes head to Las Vegas' Sands Hotel where Ricky and his orchestra are performing. Lucy and the rest of the gang (including Fred MacMurray) catch the uranium hunting bug, but it's every man for himself as the race is on to see who will be the first to claim $10,000. MacMurray's wife June Haver also guest stars.

Lucy pesters Ricky about getting a horse for Little Ricky but he refuses because a horse is too expensive. She ends up winning a horse after entering a contest and there's a lot of horsing around as she now has to figure out a way for Little Ricky to keep the horse without sending the family to the poor house. Harry James and Betty Grable guest star.

Lucy and Ricky are about to go on a "second honeymoon," but it falls through when Ricky has to do a TV show. Can Ricky and Lucy put the romance back into their marriage? Fernando Lamas guest stars as himself, assuming the role as the Ricardos' unlikely marriage counselor.