Most of the parents of The Hopkins Academy PTA test positive for STDs and is revealed that Frank had extramarital affairs with all infected females. Ian makes friends in jail, and continues his Gay Jesus antics inside. Debbie fights for equal pay at work after finding out she was being paid less. Lip juggles taking care of Xan. Carl has to prove himself at military school, while Kassidi is waiting for him outside the school.

Fiona makes a play for a risky investment opportunity, ignoring Ford’s advice. Frank discovers the financial incentives of local politics. Carl bolsters his West Point application in unexpected ways. Debbie struggles to find allies in her battle against sexual harassment. Ian is overwhelmed by the growth of the Gay Jesus movement. Kev and V try to find the perfect preschool for the twins.

Frank faces obstacles in his new role as a campaign manager. Fiona prepares to close her real estate deal. Carl enlists V to help him get a West Point recommendation from a congressman. Xan’s medical emergency puts Lip in a compromising position. Debbie gets closer with her partner in crime. Ian embarks on a spiritual journey.

Election day puts Frank and Fiona in a head to head battle as they each try to round up votes for their candidates. Lip has to make an important choice about Xan’s future. Debbie gets in over her head with Alex. Carl’s killer instinct is put to the test. With his trial looming, Ian struggles to decide how to plead. 100th episode!

Frank's new liver medication comes with tragic side effects. Ian tries to get away from Fiona's hovering. Lip has to keep himself occupied during a day of temptation. Carl makes a connection at a West Point mixer. Debbie tries to repair things with Alex.

Frank employs Liam to help him chase down a romantic connection. Lip spends the day wrangling an alcoholic actress who hired him to be her sober companion. Fiona struggles to keep up with the demands of her new investment as Ford pushes her to get serious about their relationship. Kev and V run into trouble at the twins' preschool when show and tell goes awry.

Debbie finds Fiona at a low point and helps her pick up the pieces as Fiona continues to face pressure from Max Whitford on her investment hubris. Tami stumbles back into Lip's life. Frank enjoys the honeymoon period of his relationship with Ingrid, but reality interferes soon enough. Kev and V disagree about the future of their family.

Fiona's downward spiral continues and Debbie steps in to pick up the slack at the Gallagher house. Ingrid ropes Frank into fulfilling her lifelong dream. Tami shows Lip a different version of adulthood.

Frank searches for ways to finance Ingrid’s vision for their future together. Fiona’s anger issues cause problems at Patsy’s. Lip is forced to confront his real feelings for Tami. Kelly’s father attempts to get in the middle of her relationship with Carl. Kev and V realize they are in over their heads with their latest fostering endeavor.

Frank meets his match in a fellow participant in the Hobo Loco competition. Fiona has a dark encounter at Patsy’s that scares her into cleaning up her act. Debbie throws herself into home improvements as she gets closer with Kelly. Carl gets a job that is more dangerous than it looks. Lip sees another side of Tami when they spend the day together.

The finals of the Hobo Games have arrived, and Frank faces off against his friend and greatest opponent while Ingrid grows anxious about his commitment to their future family. Lip prepares to officially adopt Xan, but his plans collide with Fiona’s partying. Debbie starts developing feelings for someone surprising, and Carl excels at the shrimp shack.

When a blackout hits the South Side, Kevin and Veronica come up with a plan to bring the neighborhood together. Carl grows suspicious of Debbie’s attempts to get closer with Kelly. Fiona receives guidance from an unexpected person and Lip has to deal with the fallout from Xan’s DCFS visit.

Frank’s injury gets in the way of everyone’s plans as Fiona attempts to get her life back on track and Lip grows frustrated with his relationship with Tami. Carl gets some bad news about his future, and Debbie finally makes a move on Kelly. Kevin and Veronica get in trouble at the twins’ preschool.

As the Gallaghers decide what to do with a bedridden Frank, Fiona has to make a decision about her future. Carl and Debbie share their heartbreak together. Lip has to deal with a distressed Tami.