Halstead returns to Med to help Goodwin with a secret investigation. Archer and Charles deal with twins who insist on being identical inside and out. Stevie and Dylan treat a young patient with sickle cell anemia.

Vanessa and Archer disagree on how to handle the victim of a motorcycle accident. Scott and Charles deal with a UNICEF negotiator with repressed trauma. Hammer and Halstead treat a high schooler with Addison's disease and a clingy mother.

Scott and Will deal with a dishonest patient whose lupus is in remission. A wealthy donor makes inappropriate advances toward Stevie. Vanessa, Marcel and Daniel try to convince a young woman to have life-saving surgery.

Daniel helps Scott with a longtime patient who was recently diagnosed with schizophrenia. Stevie, Maggie and Vanessa investigate the legitimacy of a patient's cancer diagnosis. Crockett is caught off guard. Will pitches a new medical technology.

Scott and Daniel treat patients suffering from glass child syndrome and misdiagnosed ADHD. Crockett has to navigate hospital politics when he cares for a surgeon's daughter. Will and Stevie must lay egos aside to help save an elderly patient.

Stevie's worlds collide when her mother becomes her patient. Scott's history with the father of a patient interferes with his perception of a case. Crockett's allegiances are challenged when his patient's liver is a potential transplant match.

Marcel helps Blake replace a patient's liver. Taylor tries to prove herself. Will continues to pursue the truth about Cooper. Ethan gets closer to returning to life in the ED.

Scott's loyalty to Med and the police department is challenged. The annual random drug testing puts a doctor's career in jeopardy. Choi tries a risky old-school method on a patient. Halstead helps Hammer search for her mother.

The outcome of Halstead's investigation weighs heavily on his mind as he works with Scott to save an infant. Hammer and Taylor both struggle to keep their secrets. Marcel and Blake work with Abrams to save a patient in need of a liver transplant.

In the aftermath of the Vas-COM scandal, Goodwin clashes with the hospital’s new compliance officer. Marcel and Blake try to save a patient who has a son with severe autism. A patient’s son lies to his father about his diagnosis.

Marcel and Blake clash with Shentu when a famous football player needs a liver transplant. Scott is reunited with old friends when their son breaks his arm. Hammer and Charles work together when a patient falls ill after back-alley plastic surgery.

Halstead and Hammer get stuck in the middle of a marital face-off. Blake’s entire surgical team mysteriously collapses during a liver transplant. Charles encourages Choi to reconcile with his father.

Scott and Archer diagnose a pregnant woman with a serious infection. Maggie receives shocking news. Halstead and Charles question an elderly patient's Alzheimer's diagnosis. In an effort to help a patient, Marcel takes a risk.

Goodwin assigns Med's new compliance officer to a patient with a long-hauler COVID condition. Maggie helps Halstead treat a patient who's been in an iron lung for 60 years. Hammer learns hard truths about her mother.

Scott suspects his patient may be a drug dealer. Halstead must decide how to spend his whistleblower settlement. Charles and Taylor help a patient who believes she's infested with parasites. Marcel and Blake are paired with an arrogant surgeon.

Halstead helps a patient with long-haul COVID-19 symptoms. Taylor reflects on her dating life when she learns that a patient's daughter is having an arranged marriage. A new family is born out of tragedy.

Rival gangs bring their war to Med. Will and Charles work with a teenage brain cancer patient who’s refusing treatment. Tensions run high in the OR when a patient's transplanted uterus fails, forcing Crockett and Blake to decide whether to try another transplant using a uterus from the patient's sister.

Archer and Asher clash over a patient with close ties to Goodwin. After a patient is shot during a home invasion, Scott and Marcel help with the investigation. Maggie and Halstead work to protect a patient who is in the country illegally.

Halstead and Asher work to save a surrogate's baby. Charles cares for a patient on a hunger strike. Choi and Archer help a patient with ties to Choi's late father. Scott and Maggie are stumped by a drunk patient who claims to be sober.

Dylan helps the daughter of a mob boss. A grandmother comes to Med desperate to save her grandson. Ethan struggles with some shocking news about his father. Will and Vanessa care for Maggie’s high school classmate.

Scott and Choi treat a patient shot during a drug raid. Charles and Taylor work together to properly diagnose a motivational speaker. Halstead and Asher turn to Marcel for help with a pregnant patient.

Will and Hannah clash over a patient in need of a kidney transplant. Crockett is faced with a tough decision when Blake is in surgery. Ethan and Archer treat the son of Med's general counsel. Med's family grows.