High school student Houtarou is lost in life, unable to decide what he wants to do in life. He is searching for his "Gotcha". He finds Hopper1, a chemy who is then joined by Steamliner. The two lead Houtarou to a mysterious man, who entrusts Houtarou with the power to become a Kamen Rider.

Houtarou is introduced to the secret Alchemist Academy. However, he must pass a test to join. Rinne explains more about the Chemies and digs deeper into Houtarou's encounter with the old man.

Houtarou continues his quest to befriend all the Chemies as he meets a Chemy known as Apparebushido. A new alchemist appears and demands Houtarou hands over his driver.

Houtarou tries to uncover why Rinne is always acting so cold towards him. When the two of them are sent to another world, they must work together to escape.

A hunt for more chemys leads the academy to a professional wrestling dojo. When they come under attack, Houtarou must find a new combo in order to defeat the strong Malgam.

A mysterious man challenges Supana after tracking him down.

Houtarou becomes conflicted between his heart and the rules when a boy tries to give him a chemy he found.

Saboneedle flew out of the driver during the battle with Dragonfly Malgam. Houtarou senses something as Riku becomes more distraught than ever, asking, "Where has Sabosuke gone?" Meanwhile, Atropos suddenly appears in front of Rinne...!

Houtarou and his group from Furasu High School go on a school trip to Kyoto. Houtarou is assigned to a group study with Rinne and Kajiki, and by chance Kajiki meets a girl named Hijiri, and they hit it off. They immediately become attracted to each other. At the same time, one of the Three Dark Sisters, Clotho, was also sighted in Kyoto in order to obtain something. But Clotho happens to see Houtarou and the others, and in her anger, she creates a new Malgam...!

Hijiri, whom Kajiki is in love with, has a boyfriend! Although Kajiki is depressed, he learnt that Hijiri boyfriend is most likely the remaining suspect who made his escape after Clotho attacked the police van! If that's the case, then there's a possibility that the suspect has already became a Malgam. Hijiri who is with Kajiki is in danger! Houtarou and Minato start searching for the suspect together, but...!

Clotho captures a Level 10 Chemy for the Three Dark Sisters and subjects it to their creepy experiments, bringing them closer to completion of "something". Meanwhile, Kugimiya and Harima from the Alchemys Union arrive at the academy and warn the students that there may be a mole within their ranks. However before he begins investigating on who the possible mole is, he heavily criticizes Houtarou's fighting style as a Kamen Rider.

The spy was a messenger from the Alchemy Union, Investigator Shiori Harima! Anger boils inside Houtarou as she treats Kemmie like trash. However, the three dark sisters appear and the members of Alchemy Academy are in the biggest crisis! A fragment of Malgam, a mass of human malice. System information of “Gatcha Driver” and the powerful power of “Level Number 10”! The actors are ready. Holding the completed "Dreaddriver" in hand, Atropos smiles fearlessly. He sets his sights on the only young experimental subject. "From now on, your handwriting will be Destroyer of Darkness."

Sabimaru-senpai has gone. Houtarou regrets his immaturity. Weak, fleeting, and endless suffering. The harsh reality of battle stands in front of the young alchemist. nevertheless. --Still! I don't want those fun times to be in the past! The key to saving Sabimaru is where his thoughts go. My dream Chemie, “UFOX”! Gather your friends and call the UFO. Wear the power of level number 10 and change now! Super Gatchard! Run instead of worrying! Ichinose Houtarou!

Kemmy can eat people! ? A new level number 10 appears in front of Houtarou and his friends who have successfully become friends with UFOX. Its name is “XX-Rex”! However, the X-Rex has a surprising habit of eating humans. Leaving it unattended is dangerous. Houtarou runs into Gotcha, but wonders why he would do such a thing. Meanwhile, there is another shadow chasing X-Rex. They are occult writer Manabe and his daughter, Sawa. Rinne begins to identify with Sou, who is thinking about her father. But then, the evil hand of the Three Dark Sisters approaches again...! The strongest dinosaur level 10, what is its true meaning? ?

Why do X-Rex eat people? The reason is curiosity about people. Because of their ability to see into the memories of the people they ate, they satisfied their curiosity by eating the people they were interested in. Houtarou, who was able to realize the true meaning, got X-Rex as well! Use the Super Gatchard Cross X-Rex to rush to Rinne and the Mabe family who are being attacked by the Three Dark Sisters! However, Gatchard defends himself against the onslaught of the three sisters. Atropos tries again to torture Rinne, who cannot use alchemy. Meanwhile, the Mabe family is also under the influence of evil...! It's bad if it stays like this! ! At that moment, everyone's voices reached Houtarou's ears. Turn everyone's thoughts into power, protect everyone, and Gatchard! Finally, it's time for Rinne to fight back...! ?

Be careful at Christmas! UFO-X, X-Rex... and Houtarou and his friends, who joined forces with Kamen Rider Geetz and others, made six new Level 10s at once. While everyone was in high spirits, the black steel spanner was also moving. Kyoka Edami. With her appearance as Spanner's guide, the story begins a new phase. And disaster awakens. The mythical monster ``Yamata no Orochi'' A monster resembling that giant snake fills the sky, and a darkness greater than the three sisters stands in front of Houtarou and his friends. The name of this disaster is "Grion". Kamen Rider Gatchard's biggest crisis is now upon us! !

The new year is over and the new year is here. While Houtarou was serving New Year's food in the kitchen, he was thinking about the orange gatchado that suddenly appeared at Christmas. Who the hell is he...? On the other hand, behind the scenes of Glion's revival, a person is showing signs of movement... With the appearance of Malgam and other things, the atmosphere gradually becomes uneasy, and a surprising development awaits Houtarou and his friends.

Alchemy Academy and Houtarou and his friends have lost the important figure of Minato. Houtarou loses his path and is at a loss. Renge tries to give up on becoming an alchemist. And Sabimaru can't stop it. While each of them is in conflict, Moon Margam's evil hand is once again... However, with Houtarou's current strength, Margam cannot be defeated. Receiving the teachings of the orange Gatchard who reappeared, Houtarou decides to find a way to defeat Malgam with his own power, and is time-leap into the past! ? A secret was hidden behind the time leap. Will Houtarou be able to defeat Malgam and get back on his path? ?

The Kitchen Ichinose Alliance is formed, and Houtarou and his friends are in high spirits. However, Rinne is the only one who cannot survive the excitement. Is her current behavior really the right thing to do for someone who should have cherished the ``rules''? As she worries about this, Minato appears before her. "Kudou, please come back to the academy." As an alchemist, that must be the right thing to do, right? Rinne is shaken by a question from her former "teacher." What is right for me? Meanwhile, Atropos, accompanied by the ferocious Malgam, suddenly attacks. He thrusts that blade at the troubled Rinne! "Rinne-chan, will you die today?" What does the girl see in that little devil? Now, the power sleeping inside Rinne is awakened! Transform! Kamen Rider Majed! !

The black steel spanner was impatient. Ichinose was only an amateur. Kudo was supposed to be protected. Both of them obtained powers stronger than themselves as ``Kamen Riders.'' More power... More strength! ! Just as Spanner looks like that, her parents, who were supposed to be on a long journey, suddenly appear. Spanner smiles as he reunites with his parents. Maybe there is a place I should protect, a place I should return to. However, that was a pale dream given to me by an angel. The most vile and cruel trap for a spanner. When the messenger of darkness, the angel of darkness, laughs, the wrench of a spanner echoes in vain.

The black steel spanner was engulfed by its own "black flame" and was tragically turned into Malgam. In the past, he saw his parents murdered with his own eyes. Despair and hatred bring their parents back to life and have them killed again and again in front of their eyes. Anger towards his master who hid his past and locked away his power for 10 years. Helpless, Houtarou and his friends help Kyoka create a screwdriver and think about their only hope of saving Spanner. Spanner vows to take revenge on Glion even if he becomes Malgam. What appeared in front of him was his former senior wearing a dread mask. Who will control their power and win the battle? And what is the outcome of the spanner that is eaten away by black flames...

One day in the kitchen. The appearance of a lotus flower creates a mesmerizing and strange atmosphere. It seems that they are in love, so Houtarou and his friends decide to follow him in order to find him. Furthermore, in a certain town. There is a mysterious man with good looks who exudes charm. Its appearance is... the Zukyunpire of occult chemistry...! ? He seems to be planning something with a large group of people. What exactly is that purpose? Meanwhile, Kuroto, who has a strong fighting spirit, is given a certain power by Glion. She also seems to have something planned... Find out the fate of Renge's love, Kuroto's plan, and the mystery of Zukyunpire!

If this continues, Full Power Zukkyun will accumulate! ! ! ! Houtarou and his friends try to stop the invasion of Full Power Zukkyun due to the power of Chemie, who fascinates people, and Zukkyun Pier. Why is Zukyunpire, who is supposed to be Chemie, causing people pain! ? When the truth about the Zukyun Pier is revealed, the world is now covered by the biggest Zukyun in history! ! Vampire is the prince of the moonlit night. Now is the time to fight back with the power of the moon! Activate! Majed Moon Cerberus!

The Kitchen Ichinose Union was having a peaceful time when a bolt of heaven hit! ! Surprisingly, all the data that Sabimaru had archived so far has disappeared! This must be the work of the eraser Kemie "Keszo" who was supposed to have gotten it. Let's all find Kesuzo hidden in the clouds! ! ...That's it! ? Not only the data but also all the cards disappeared! ? And Houtarou's ring has changed too! ? In the end, even the steam liner has changed in appearance! ? ! ? What happened? Forbidden power, Dread Ishiki, ancient Malgam! Everything is about to take a sudden turn! ! Don't miss the exciting developments! !

However, the effects on Houtarou's body are immeasurable, and Rinne and her friends are worried about Houtarou's health. What appeared in the midst of all this was Fuga Kudou. Kemie and the others are still taken by Fuga and Glion.