With no arrest having been made years after a real estate agent's murder, frustration continues to mount among her family and friends; detectives connect a series of seemingly random crimes to crack the case of a missing young man.

Police link a filmmaker who is obsessed with the show "Dexter" with a man's disappearance.

The disappearance of two teenagers brings together two families in a common journey for justice.

An Easter Sunday celebration in 2006 turns tragic when Wayne and Sharmon Stock are murdered. Correspondent Keith Morrison traces the search for justice in the case.

A young devoted Illinois father, Steven Watkins, finds the woman of his dreams, who's beautiful and comes from a tight-knit, religious family. NBC News' Rob Stafford reports

"Rescue on the Mountainside" Ann Curry reports on the August 9, 2010 plane crash in Alaska that killed Senator Ted Stevens and the heroic efforts of the crash survivors and rescuers who responded quickly to the crisis

"Blind Justice" Keith Morrison investigates the murder of Susan Sutton and the blinding of her husband John in their Coral Gables, Florida home on August 22, 2004.

Kate Snow investigates the disappearance and murder of Cher Hughe, a resident on the tropical island Bocas del Toro off the coast of Panama.

A teenager disappears from her friend's house before being found dead.

An Air Force captain is shot dead, leaving police to suspect his wife and her sharpshooter lover.

Correspondent Kate Snow explores the courtship between Prince William and Kate Middleton in a report that features clips of Middleton and interviews with friends. Included: the couple's first meeting is recalled.

A teenage girl is involved in a murder mystery after her older boyfriend is attacked and dies.

George Clooney embarks on a fact-finding mission across war-torn Sudan.

Previously unknown details of the Elizabeth Smart abduction, reported by Natalie Morales; investigators fear the case of a murdered businessman may go unsolved despite their continued efforts, reported by Chris Hansen.

The remains of 11 female bodies are found in the desert outside of Albuquerque, New Mexico.

Ann Curry travels to the remote hills of Haiti with a group of American volunteers fighting against the cholera outbreak.

Dateline NBC confronts criminals who they have caught on hidden camera

When a "dog trainer to the stars" disappears, his friends and co-workers fear the worst. Keith Morrison follows all the twists and turns in the case as investigators track down the suspect with the help of two witnesses who were in the right place at the right time. Keith Morrison reports.

Actor Michael Douglas discusses his battle with cancer; former President George H.W. Bush's foreign policy team; Tucson, Ariz., shooting survivor Suzi Hileman.

“Written in Blood" Dennis Murphy reports from Michigan on the murder of two parents and the investigation into their son.

Hidden cameras reveal scams including a psychotherapist with a dark secret, fortune tellers and air duct cleaning companies.

“Bringing Brooke Home" Kate Snow reports on the disappearance and murder of Brooke Wilberger.

Aron Ralston, whose climbing-accident story inspired the movie ``127 Hours,'' talks about his life after the incident.

An attractive nurse, Sherri Rasmussen, is murdered in her own home in 1986. There are few clues, except one: a bite mark containing saliva found on Sherri's arm. But it's of little use because DNA testing is not yet available. “Internal Affairs" Josh Mankiewicz follows a cold case to its conclusion as the Los Angeles Police Department investigates its own officer for a murder.

“Inconceivable" Meredith Vieira reports on a mother who discovered she was carrying another couple's embryo.

A man is fatally poisoned by medication for a disease he didn't have, casting suspicion on his nurse wife.

Musician Janet Jackson discusses her childhood, self-esteem issues, career highs and lows, and her new book "True You."

Detectives take another look at a 20-year-old murder and discover the evidence points to one of their own.

Actress Suzanne Somers speaks with Dr. Nancy Snyderman about alternative cancer treatments.

Rachel Wade reveals the dynamics of online confrontation between herself and Sarah Ludemann, both of whom were in love with the same man but have only met once in real life

A top-ranking officer in the Canadian military pleaded guilty to a number of crimes, from home invasions and lingerie theft to murder.

A look at actor Charlie Sheen's home life at his estate. Correspondents Jeff Rossen reports.

Hidden cameras reveal how teens react to different bullying situations.

A divorced mother hires someone to kill her ex-husband. Dateline's Josh Mankiewicz delivers an update from San Diego about the story of a mother and grandmother who emerge from deep adversity..

Dateline’s Keith Morrison retraces the steps taken by a retired detective to dust off a cold case murder with the help of a photographer’s diary.

A young woman is found severely injured in the middle of the road, but her injuries have robbed her of her memory of what happened to her. Also, Keith Morrison reports on a woman kidnapped as a child and raised by her kidnappers searches for her real identity.

Dennis Murphy investigates the mysteries surrounding the shooting deaths of two family members in a still Georgia hamlet.

Correspondent Hoda Kotb delves into a four-year international custody battle.

When Amber Dubois vanished in San Diego County, a search turned up nothing. Then, a year later, Chelsea King disappeared in a neighboring town. Tonight, Keith Morrison reports on the mystery of the missing California teens.

Reporter Keith Morrison explores the plight of unwanted children in Moscow, recounting the story of an institutionalized boy whose life took a positive turn after years of rejection.

Rob Stafford investigates the cold-blooded slaying of an expectant mother. In a second report, Keith Morrison tracks the work of a dauntless detective and a determined attorney to solve the cold-case killing of a 21-year-old woman.

Chris Hansen files a report on Mexico's drug war. Hansen joins with Mexican federal officers on a secret assignment to capture kingpins and relates the story of a hit man leading a double life. Also: a woman who sacrificed all to battle corruption.

Events that lead to a woman being found on the side of the road covered in blood and brain damaged.

NBC’s Dennis Murphy traces the journey of Kate Middleton from commoner to Her Royal Highness.

The impact of the recent tornadoes, severe thunderstorms and flash-flood warnings in the United States; reports from London include behind-the-scenes coverage of the royal wedding.

A man and his son are shot to death, tearing their family apart.

A man who was arrested and tried three times for the death of his wife of four months talks about the case. Dennis Murphy reports.

David Goldman, whose five year battle for custody of his son made international news, talks about life since being reunited with his child.

A doctor disappears while on vacation with his wife, leaving her $6 million in debt.

A detective and a deputy district attorney solve the decades-old murder of a young woman at a fast-food restaurant.

The investigation into the murder of a pregnant woman leads to a former pro football player.

Chris Hansen visits a shop in New York that sells bath salts, a new designer drug.

Keith Morrison reports the story of an Oklahoma pastor's son and daughter who endure a remarkable road to recovery after witnessing a terrible family tragedy.

A man is shot to death on a family hunting trip in Newfoundland.

A circle of friends from a high school in Miami are about to embark on a new beginning, all heading off to college for the first time. But when one is left behind, he surprises them all with a last minute decision. Dennis Murphy reports.

Josh Mankiewicz probes the cold-case murder of a casino-sales executive.

New details and courtroom dramas key Dennis Murphy's update on the Caylee Anthony case. Anthony's young mother, Casey Anthony, is accused of murdering the toddler in 2008.

A man who was arrested and tried three times for the death of his wife talks about the case.

Lester Holt takes viewers into Chicago communities, children who grow up quickly and die young.

A young detective investigates a college student's death; chronicling the events of the Casey Anthony murder trial.

When a woman goes missing in a small town in rural Michigan, her husband becomes the primary suspect. But eyewitnesses and surveillance cameras support his alibi that he was in Virginia the day she disappeared - more than 700 miles away. Dennis Murphy reports.

A year-long investigation into children migrant workers.

A woman finds her way back to her family after being kidnapped 30 years earlier.

Chris Hansen goes face-to-face with a man, who along with other conspirators, cheated a Connecticut woman out of her life savings through an internet scam.

The 2004 murder of a young casino sales executive in Las Vegas.

A former homecoming queen comes under suspicion after her husband is found stabbed to death and an affair with the local youth pastor is uncovered.

Brian Williams documents a day behind-the-scenes on Capitol Hill where viewers will get an unprecedented look at life under the U.S. Capitol dome.

Police doubt an Ohio doctor's story about events leading to his wife's death.

Tom Brokaw reports the story of three different families throughout the war in Iraq.

A couple's romantic night at the Hudson Palisades ends in a tragic fall, leaving officials questioning whether or not it was an accident. Andrea Canning reports.

Lester Holt reports the story of three American women who face the Great Recession and their own worst fears.

Former Vice President Dick Cheney discusses his new memoir with Jamie Gangel; Grammy award winner Miranda Lambert is interviewed by Hoda Kotb; 12-year-old author of "Heaven is for Real" sits down with Hoda Kotb to hear about his trip to heaven.

Tom Brokaw, recaps some of the most powerful stories reported by NBC News in the days and months following the tragic assault on our nation.

Police investigate the shooting death of a man who was in bed with his wife.

A woman disappears while on her morning jog.

After a woman goes missing, authorities suspect the man responsible was reenacting a horror movie.

Police solve a case of a teenager who disappeared from her friend's house before being found dead; a case of a love triangle involves an Air Force captain, his wife and her lover.

A woman claims to have been abducted from her multimillion-dollar home.